The following evidence based practice database feature both qualitative and quantitative peer reviewed article after selecting the best articles related to decreasing Central Line Associated Blood Stream Infection (CLABSI) in oncology nursing with a special focus on the treatment and care for cancer patients. According to the center for disease control in the United states, the most common healthcare associated infection is the CLABSI which reports about 50%  of all ICU patient that require a central line, having high cases of CLABSI infections. As a Nursing practitioner to understand the nature leading to CLABSI incidences it is important to conduct a review on strategies.  In most cases, the catheter on the central line is known to puncture the skin which allows for bacterial and function infection to enter the human body. After the infection enters the body, this can spread to the patient’s blood stream leading to hemodynamic changes that could possibly head to death of the patient. In most cases, proof of infection is found in the recovery of a pathogen from blood culture and patients that suffered from central line.  

Peer review findings

Altounji et al., (2020) in a qualitative literature review study reports that most children receiving cancer treatment will require a central venous catheter (CVC) which continue to put them at risk of CLABSI. According to the researchers, as patient are discharged home with a CVC, it is important that a follow up by nurses is done to ensure that CVC is maintained. The article is very important as it suggests the relevance of education sessions with the patient family using a step by step handbook among other materials that equip caregivers with the right skills and checklist of competency.  Base on the study, it is evident that the clinical significance in reducing  home based acquired CLABSI can produce positive  regard on the patient outcomes through  a reduction of mortality and morbidity thus reducing costs of care and length of stay in hospital. 

Inman & Torres, (2020) in a focused group qualitative study argues that blood cultures usually will be contaminated during the pre-analytic phases in regard to collection that leads to downstream ramifications. The study is important as it provides a summary of performance improvement when it comes to factors that contribute to a reduction in the blood culture rates.  The article is thus important as it meets the goal of the study to reduce their rate of BCC through analyzing, pre and post intervention data.  Based on the study, it is possible to achieve these rates with the support of multi-disciplinary team. It is thus important for nurses to benchmark as part of their practice if they are to achieve a sustainable BCC levels. 

(Chaves et al., 2018) in a quantitative study reports that CLABSI is often made of an important cause of hospital acquired infection related to mortality, morbidity and cost. The study provides a guideline with recommendations for the management and diagnosis of CLABSI in adults. Criteria for the study included use of short term peripheral venous catheter, and long term CVC among other criteria’s.  The article is important as it is formulated in regard to amount of evidence based practices. Also the recommendation is made in regard to the diagnosis of CLABSI by establishing various clinical situations where a conservative diagnosis related to CLABSI can be feasible.  Among the notable areas in the study also is the importance of pathogen specific treatment and empirical therapy during this time. 

Patel et al., (2019) in a quantities study on the National Intervention prevention of CLABSI informs that it is important to understand the impact of multimodal intervention in institutions that are common with healthcare related infection.  The study was observational involving two target hospitals one with tertile of performance for the clostridioides difficile infection while the other one looked at care related to CLABSI. According to the results of the study from 2016 to 2018 it was evident that there was still need to educated nurses on the implementation of CLABSI prevention methodologies. Also during the period of –pre invention to was realized that the rates of clabsi will reduce. This is important as it provides the need for organization to provide orientation and education for nurses on the issue of CLABSI management and prevention. 

Aloes, (2019) in a comparative study found that using the Center for Disease control in prevention of CLABSI complications is often very important   in ensuring improvement of care and prevention of complications.  It is however to verified if nursing students are provide with education regarding the guidelines.  The study is important as it provides and assessment on the knowledge of nurses in educating their patients on the importance of hygiene and do not bring bout jokes. 


The above evidenced pare looked the issue of CLABSI and nursing participation in the reduction of such incidences.  The article share are a strong ground for future studies on the same.  It is important to ensure I sally.


Aloush, S. M. (2019). Lecture-based education versus simulation in educating student nurses about central line–associated bloodstream infection–prevention guidelines. Journal of Vascular Nursing, 37(2), 125-131.

Altounji, D., McClanahan, R., O’Brien, R., & Murray, P. (2020). Decreasing central line–associated bloodstream infections acquired in the home setting among pediatric oncology patients. Journal of Pediatric Oncology Nursing, 37(3), 204-211.

Chaves, F., Garnacho-Montero, J., Del Pozo, J., Bouza, E., Capdevila, J., De Cueto, M., Domínguez, M., Esteban, J., Fernández-Hidalgo, N., Fernández Sampedro, M., Fortún, J., Guembe, M., Lorente, L., Paño, J., Ramírez, P., Salavert, M., Sánchez, M., & Vallés, J. (2018). Diagnosis and treatment of catheter-related bloodstream infection: Clinical guidelines of the Spanish society of infectious diseases and clinical microbiology and (SEIMC) and the Spanish society of Spanish society of intensive and critical care medicine and coronary units (SEMICYUC). Medicina Intensiva (English Edition), 42(1), 5-36.

Inman, T., & Torres, E. (2020). Blood culture collection teams reduce contamination rates and reduce central line associated blood stream infections. American Journal of Infection Control, 48(8), S40.

Patel, P. K., Greene, M. T., Jones, K., Rolle, A. J., Ratz, D., Snyder, A., Saint, S., & Chopra, V. (2019). Quantitative results of a national intervention to prevent central line–associated bloodstream infection. Annals of Internal Medicine, 171(7_Supplement), S23.


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